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SAVE-THE-DATE: HD Information Evening, 7 April 2025

Huntington Disease Center in Lund is inviting you to an information evening on 7 April 2025, 18.00-20.30 in the Belfrage lecture hall on BMC D15 in Lund. The evening will include update on clinical trials and current research status in Sweden and internationally, as well as talks on different aspects on Huntington disease: from social interaction to difficulty swallowing, dysphagia. Representative

https://www.huntington-research.lu.se/article/save-date-hd-information-evening-7-april-2025 - 2025-10-25

Work in progress: International guidelines for treatment of psychiatric symptoms

Development of international guidelines for treatment of psychiatric symptoms in advanced Huntington's disease is in progress within the European Huntington's Disease Network (EHDN). The working group focusing on "Behavioural Phenotype” in Huntington's disease is addressing these guidelines. As part of the work, some members of the group recently met in Amsterdam, together with colleagues from USA

https://www.huntington-research.lu.se/article/work-progress-international-guidelines-treatment-psychiatric-symptoms - 2025-10-25

Podcast about being a young relative of an HD-patient

The month of May is Huntington’s Disease Awareness Month and 15 May was Huntington Awareness Day. Åsa Petersén was invited to take part in a podcast about the disease, together with Jozefine, who is a carrier of the gene and related to a person diagnosed with HD.The podcast is produced by YTAN, Young Together Against Neurodegenerative Diseases, a digital platform for young relatives of persons wit

https://www.huntington-research.lu.se/article/podcast-about-being-young-relative-hd-patient - 2025-10-25

New paper from TNU published!

The protein TDP-43 is involved in different neurodegenerative diseases, and Åsa Petersén and Sofia Bergh have investigated whether the protein harms the hypothalamus. Investigating if augmenting the quantity of the protein TDP-43 in the hypothalamus would lead to changes in the hypothalamus, emotional changes and metabolic problems was the aim of the new article from the TNU research group.Read mo

https://www.huntington-research.lu.se/article/new-paper-tnu-published - 2025-10-25

Petersén guest editor of Journal of Huntington's Disease

Åsa Petersén and Mahmoud A Pouladi are guest editors of the Special Issue: Glia and non-neuronal cells in Huntington's disease that was published now in August. The Special issue on Glia and non-neuronal cells in Huntington's disease holds six expert review articles. The understanding how glial and other non-neuronal cells shape HD pathology is expanding amongst researchers in the field.The topics

https://www.huntington-research.lu.se/article/petersen-guest-editor-journal-huntingtons-disease - 2025-10-25

Petersén gives a talk at a symposium on neurodegenerative disorders in Vancouver, Canada on Sept 8, 2025

Petersén will give a talk on her work on Huntington disease at a symposium on neurodegenerative disorders at the University of British Columbia in Vancouver, Canada on September 8, 2025. There will also be a meeting for Petersén and other partners in the JPND funded delCAA-HD research team to discuss progress of the international collaborative research efforts.

https://www.huntington-research.lu.se/article/petersen-gives-talk-symposium-neurodegenerative-disorders-vancouver-canada-sept-8-2025 - 2025-10-25

Visit by the European Huntington Association

When in Sweden for their annual meeting, members of the European Huntington Association paid a visit to Lund on 28 August 2025. There they met with Åsa Petersén and Camilla Svensson, registered nurse, also working at the HD Clinic at Skåne University Hospital (SUS) in Lund, together with Åsa. Åsa showed them around the lab, demonstrated samples and talked about her research. The EHA team also got

https://www.huntington-research.lu.se/article/visit-european-huntington-association - 2025-10-25

Sofia Bergh will present poster at TDP-43 conference

On 9-11 September 2025 the Arturo Falaschi Conference “2nd biennial conference on TDP-43 function and dysfunction in disease” will be held in Trieste, Italy. Sofia Bergh will present her poster with the findings published earlier this summer in the article “TDP-43 overexpression in the hypothalamus drives neuropathology, dysregulates metabolism and impairs behavior in mice”.Link to the conference

https://www.huntington-research.lu.se/article/sofia-bergh-will-present-poster-tdp-43-conference - 2025-10-25

Updated information on HD on the National Board of Health and Welfare's webpage

The National Board of Health and Welfare in Sweden has published updated information on Huntington disease on its’ webpage. These recent revisions of the text have been made by Professor Åsa Petersén, Lund University.Link to the National Board of Health and Welfare’s webpage – in Swedish only (opens in a new window).

https://www.huntington-research.lu.se/article/updated-information-hd-national-board-health-and-welfares-webpage - 2025-10-25

Perspective on recent positive topline results from gene therapy trial

Professor Petersén comments on the recent positive topline results from a clinical trial with gene therapy in Huntington disease presented in a press release from uniQure. Last week, positive topline results from a clinical trial with gene therapy in Huntington disease were presented in a press release from uniQure. The news hit the headlines and spread fast through the HD community. Read Professo

https://www.huntington-research.lu.se/article/perspective-recent-positive-topline-results-gene-therapy-trial - 2025-10-25

TV4 news piece on HD gene therapy trial

The Swedish channel TV4 published the news on the HD clinical trials that were positively described in media in late September. Professor Åsa Petersén was interviewed about the findings by TV4 and she emphasizes the need for cautiousness when interpreting the results, as they are not yet published in a scientific magazine or reviewed by researchers not involved in the study. Link to the article on

https://www.huntington-research.lu.se/article/tv4-news-piece-hd-gene-therapy-trial - 2025-10-25

TNU:s research selected for oral presentation at the EHDN meeting

Dr Rana Soylu Kucharz presented her recent project with the title "Striatal Neuropathology induced by Hypothalamic Overexpression of Huntingtin Fragments using Adeno-associated Viral Vectors in Mice” as an oral presentation in the Short Communication session at the EHDN meeting in the Hague, the Netherlands, in September 2016.

https://www.huntington-research.lu.se/article/tnus-research-selected-oral-presentation-ehdn-meeting - 2025-10-25